Aldehyde Detection in Electronic Cigarette Aerosols

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Aldehyde Detection in Electronic Cigarette Aerosols

Acetaldehyde, acrolein, and formaldehyde are the principal toxic aldehydes present in cigarette smoke and contribute to the risk of cardiovascular disease and noncancerous pulmonary disease. The rapid growth of the use of electronic cigarettes (e-cigarettes) has raised concerns over emissions of these harmful aldehydes. This work determines emissions of these aldehydes in both free and bound (a...

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Highly reactive free radicals in electronic cigarette aerosols.

Electronic cigarette (EC) usage has increased exponentially, but limited data are available on its potential harmful effects. We tested for the presence of reactive, short-lived free radicals in EC aerosols by electron paramagnetic resonance spectroscopy (EPR) using the spin-trap phenyl-N-tert-butylnitrone (PBN). Radicals were detected in aerosols from all ECs and eliquids tested (2.5 × 10(13) ...

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Hidden formaldehyde in e-cigarette aerosols.

1. Fencl V, Jabor A, Kazda A, Figge J. Diagnosis of metabolic acid-base disturbances in critically ill patients. Am J Respir Crit Care Med 2000;162:2246-51. 2. Adrogué HJ, Gennari FJ, Galla JH, Madias NE. Assessing acid-base disorders. Kidney Int 2009;76:1239-47. 3. Boron WF. Regulation of intracellular pH. Adv Physiol Educ 2004;28:160-79. 4. Hill AB. The environment and disease: association or...

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Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage

BACKGROUND Electronic cigarette (EC) aerosols contain unique compounds in addition to toxicants and carcinogens traditionally found in tobacco smoke. Studies are warranted to understand the public health risks of ECs. OBJECTIVE The aim of this study was to determine the genotoxicity and the mechanisms induced by EC aerosol extracts on human oral and lung epithelial cells. METHODS Cells were...

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The assessment of H2AX induction from conventional and electronic cigarette aerosols

Exposure systems have been used to assess cigarette smoke aerosols for many years, using a variety of invitro endpoints. These systems produce a more physiologically relevant test matrix compared to traditionalmethods, and as a result in vitro aerosol techniques are widely being developed. Of particular interest aregenotoxicity assays such as the H2AX assay which may be used to dete...

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ژورنال

عنوان ژورنال: ACS Omega

سال: 2017

ISSN: 2470-1343,2470-1343

DOI: 10.1021/acsomega.6b00489